node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IO98_01980 | IO98_05660 | IO98_01980 | IO98_05660 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.856 |
IO98_01980 | IO98_06835 | IO98_01980 | IO98_06835 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
IO98_01980 | IO98_14995 | IO98_01980 | IO98_14995 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
IO98_05660 | IO98_01980 | IO98_05660 | IO98_01980 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.856 |
IO98_05660 | IO98_06835 | IO98_05660 | IO98_06835 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
IO98_05660 | IO98_08550 | IO98_05660 | IO98_08550 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
IO98_05660 | IO98_14915 | IO98_05660 | IO98_14915 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
IO98_05660 | IO98_14995 | IO98_05660 | IO98_14995 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
IO98_05660 | IO98_22140 | IO98_05660 | IO98_22140 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.921 |
IO98_05660 | gltX | IO98_05660 | IO98_05665 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.739 |
IO98_05660 | mutL | IO98_05660 | IO98_21400 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.871 |
IO98_05660 | uvrB | IO98_05660 | IO98_11690 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.910 |
IO98_05660 | uvrC | IO98_05660 | IO98_21095 | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.779 |
IO98_06835 | IO98_01980 | IO98_06835 | IO98_01980 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
IO98_06835 | IO98_05660 | IO98_06835 | IO98_05660 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
IO98_06835 | IO98_08550 | IO98_06835 | IO98_08550 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
IO98_06835 | IO98_14915 | IO98_06835 | IO98_14915 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.890 |
IO98_06835 | IO98_14995 | IO98_06835 | IO98_14995 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
IO98_06835 | IO98_22140 | IO98_06835 | IO98_22140 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.923 |
IO98_06835 | mutL | IO98_06835 | IO98_21400 | Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.876 |