Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
IO98_07320MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
accD
acetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
   
  0.852
ribBA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.795
IO98_09400
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.640
IO98_05840
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
 
 
 0.590
IO98_07315
PadR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.531
IO98_00965
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.530
IO98_22455
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.529
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.521
IO98_07325
Flavin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.492
rpoC
DNA-directed RNA polymerase subunit alpha/beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.472
Your Current Organism:
Clostridium celerecrescens
NCBI taxonomy Id: 29354
Other names: ATCC 49205, CECT 954, Clostridium celericrescens, DSM 5628, [. celerecrescens, [Clostridium] celerecrescens, strain 18A
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