Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IO98_08950Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)    
Predicted Functional Partners:
IO98_10605
Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.960
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.874
IO98_08935
Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.868
IO98_00785
Chemotaxis protein CheY; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.862
IO98_16025
Anti-sigma factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
  
  
 0.861
IO98_12605
Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.859
IO98_10635
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.857
IO98_03725
Stage III sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.856
IO98_11135
Stage II sporulation protein P; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.856
IO98_08905
Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.847
Your Current Organism:
Clostridium celerecrescens
NCBI taxonomy Id: 29354
Other names: ATCC 49205, CECT 954, Clostridium celericrescens, DSM 5628, [. celerecrescens, [Clostridium] celerecrescens, strain 18A
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