Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
IO98_19620Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (773 aa)    
Predicted Functional Partners:
IO98_10550
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.903
IO98_19610
Colicin V synthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.879
IO98_00880
Molecular chaperone Hsp90; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.868
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.864
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
 0.862
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
  0.847
IO98_19850
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.841
IO98_20985
Signal protein PDZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.841
IO98_19895
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.823
IO98_00820
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.817
Your Current Organism:
Clostridium celerecrescens
NCBI taxonomy Id: 29354
Other names: ATCC 49205, CECT 954, Clostridium celericrescens, DSM 5628, [. celerecrescens, [Clostridium] celerecrescens, strain 18A
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