STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A1E_02950Polynucleotide phosphorylase/polyadenylase; COG1109 Phosphomannomutase. (515 aa)    
Predicted Functional Partners:
A1E_03805
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
  
 
 0.923
A1E_04520
Mannose-1-phosphate guanylyltransferase.
     
  0.900
miaA-2
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.774
A1E_01650
Acylglycerophosphoethanolamine acyltransferase.
  
 
 0.720
A1E_02930
KpsF protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.
   
 
 0.709
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.701
A1E_03790
Minor teichoic acids biosynthesis protein ggab (ggab); COG0463 Glycosyltransferases involved in cell wall biogenesis.
  
 
 0.675
A1E_03585
Phosphate acetyltransferase; COG0281 Malic enzyme.
  
  
 0.662
A1E_01505
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
     
 0.628
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
   
 
 0.627
Your Current Organism:
Rickettsia canadensis
NCBI taxonomy Id: 293613
Other names: R. canadensis str. McKiel, Rickettsia canadensis str. McKiel, Rickettsia canadensis strain McKiel
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.