STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SES62487.1Stage II sporulation protein GA (sporulation sigma-E factor processing peptidase); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (304 aa)    
Predicted Functional Partners:
SET41604.1
Stage II sporulation protein E.
  
  
 0.965
SES62499.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.925
SET63255.1
Stage II sporulation protein R.
 
   
 0.902
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.874
SET10241.1
Putative DeoR family transcriptional regulator, stage III sporulation protein D.
  
  
 0.854
SES86980.1
Stage III sporulation protein AA.
  
  
 0.837
SES62578.1
Sporulation protein, YlmC/YmxH family.
 
     0.825
SES62566.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.821
SES87000.1
Stage III sporulation protein AB.
  
  
 0.802
SES99961.1
Sporulation integral membrane protein YlbJ.
  
   
 0.798
Your Current Organism:
Clostridium polysaccharolyticum
NCBI taxonomy Id: 29364
Other names: ATCC 33142, Fusobacterium polysaccharolyticum, [. polysaccharolyticum, [Clostridium] polysaccharolyticum, strain B
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