grsB_1 protein (Clostridium puniceum) - STRING interaction network

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Score

grsB_1

Gramicidin S synthase 2. (575 aa)

Predicted Functional Partners:

grsB_3

0.994

lgrD_4

0.991

dltA

0.978

dhbF

0.952

grsB_5

0.920

lgrD_1

0.916

tycC_2

0.915

lgrD_3

0.905

ppsC_1

0.903

mbtB_1

0.882

Your Current Organism:

Clostridium puniceum

NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dhbF	dltA	CLPUN_43860	CLPUN_14630	Dimodular nonribosomal peptide synthase.	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	0.848
dhbF	grsB_1	CLPUN_43860	CLPUN_00970	Dimodular nonribosomal peptide synthase.	Gramicidin S synthase 2.	0.952
dhbF	grsB_3	CLPUN_43860	CLPUN_24970	Dimodular nonribosomal peptide synthase.	Gramicidin S synthase 2.	0.999
dhbF	grsB_5	CLPUN_43860	CLPUN_43910	Dimodular nonribosomal peptide synthase.	Gramicidin S synthase 2; Belongs to the ATP-dependent AMP-binding enzyme family.	0.988
dhbF	lgrD_1	CLPUN_43860	CLPUN_43690	Dimodular nonribosomal peptide synthase.	Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family.	0.999
dhbF	lgrD_3	CLPUN_43860	CLPUN_43890	Dimodular nonribosomal peptide synthase.	Linear gramicidin synthase subunit D.	0.999
dhbF	lgrD_4	CLPUN_43860	CLPUN_49010	Dimodular nonribosomal peptide synthase.	Linear gramicidin synthase subunit D.	0.999
dhbF	mbtB_1	CLPUN_43860	CLPUN_49030	Dimodular nonribosomal peptide synthase.	Phenyloxazoline synthase MbtB.	0.998
dhbF	ppsC_1	CLPUN_43860	CLPUN_24960	Dimodular nonribosomal peptide synthase.	Plipastatin synthase subunit C.	0.999
dhbF	tycC_2	CLPUN_43860	CLPUN_28120	Dimodular nonribosomal peptide synthase.	Tyrocidine synthase 3.	0.999
dltA	dhbF	CLPUN_14630	CLPUN_43860	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Dimodular nonribosomal peptide synthase.	0.848
dltA	grsB_1	CLPUN_14630	CLPUN_00970	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Gramicidin S synthase 2.	0.978
dltA	grsB_3	CLPUN_14630	CLPUN_24970	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Gramicidin S synthase 2.	0.988
dltA	grsB_5	CLPUN_14630	CLPUN_43910	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Gramicidin S synthase 2; Belongs to the ATP-dependent AMP-binding enzyme family.	0.608
dltA	lgrD_1	CLPUN_14630	CLPUN_43690	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family.	0.805
dltA	lgrD_3	CLPUN_14630	CLPUN_43890	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Linear gramicidin synthase subunit D.	0.808
dltA	lgrD_4	CLPUN_14630	CLPUN_49010	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Linear gramicidin synthase subunit D.	0.988
dltA	mbtB_1	CLPUN_14630	CLPUN_49030	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Phenyloxazoline synthase MbtB.	0.892
dltA	ppsC_1	CLPUN_14630	CLPUN_24960	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Plipastatin synthase subunit C.	0.809
dltA	tycC_2	CLPUN_14630	CLPUN_28120	D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]	Tyrocidine synthase 3.	0.972