| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB_1 | carB_2 | CLPUN_21040 | CLPUN_37470 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.785 |
| carB_1 | glmS | CLPUN_21040 | CLPUN_01320 | Carbamoyl-phosphate synthase large chain. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.863 |
| carB_1 | glnA_1 | CLPUN_21040 | CLPUN_45930 | Carbamoyl-phosphate synthase large chain. | Glutamine synthetase. | 0.867 |
| carB_1 | gltB_1 | CLPUN_21040 | CLPUN_45950 | Carbamoyl-phosphate synthase large chain. | Ferredoxin-dependent glutamate synthase 1. | 0.954 |
| carB_1 | purL | CLPUN_21040 | CLPUN_39620 | Carbamoyl-phosphate synthase large chain. | Phosphoribosylformylglycinamidine synthase. | 0.917 |
| carB_2 | carB_1 | CLPUN_37470 | CLPUN_21040 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase large chain. | 0.785 |
| carB_2 | glmS | CLPUN_37470 | CLPUN_01320 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.869 |
| carB_2 | glnA_1 | CLPUN_37470 | CLPUN_45930 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamine synthetase. | 0.894 |
| carB_2 | gltB_1 | CLPUN_37470 | CLPUN_45950 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Ferredoxin-dependent glutamate synthase 1. | 0.954 |
| carB_2 | purL | CLPUN_37470 | CLPUN_39620 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase. | 0.932 |
| glmM | glmS | CLPUN_01730 | CLPUN_01320 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.958 |
| glmM | glmU | CLPUN_01730 | CLPUN_05570 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.981 |
| glmM | gltB_1 | CLPUN_01730 | CLPUN_45950 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Ferredoxin-dependent glutamate synthase 1. | 0.424 |
| glmM | nagA | CLPUN_01730 | CLPUN_45420 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | N-acetylglucosamine-6-phosphate deacetylase. | 0.883 |
| glmM | nagB | CLPUN_01730 | CLPUN_45430 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase 1; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.884 |
| glmM | pgi | CLPUN_01730 | CLPUN_21480 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.867 |
| glmS | carB_1 | CLPUN_01320 | CLPUN_21040 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase large chain. | 0.863 |
| glmS | carB_2 | CLPUN_01320 | CLPUN_37470 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.869 |
| glmS | glmM | CLPUN_01320 | CLPUN_01730 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.958 |
| glmS | glmU | CLPUN_01320 | CLPUN_05570 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.939 |