Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
leuA_22-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa)    
Predicted Functional Partners:
dmdA
2,3-dimethylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.939
dmdB
2,3-dimethylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.938
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.930
ilvB_1
Acetolactate synthase large subunit.
 
 
 0.924
ilvH
Acetolactate synthase small subunit.
 
 
 0.916
ilvB_3
Acetolactate synthase isozyme 1 large subunit.
 
 
 0.914
hacA
Homoaconitase large subunit.
  
 0.912
ilvK
Branched-chain-amino-acid aminotransferase 2.
  
 0.907
grsB_3
Gramicidin S synthase 2.
  
 
 0.901
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.899
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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