dnaE protein (Clostridium puniceum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Clostridium puniceum

NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OOM73512.1	OOM74299.1	CLPUN_45350	CLPUN_40040	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit epsilon.	0.898
OOM73512.1	OOM74555.1	CLPUN_45350	CLPUN_37960	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit beta.	0.926
OOM73512.1	OOM75059.1	CLPUN_45350	CLPUN_34960	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit delta.	0.903
OOM73512.1	dnaE	CLPUN_45350	CLPUN_14920	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit alpha.	0.891
OOM73512.1	dnaN	CLPUN_45350	CLPUN_48940	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.926
OOM73512.1	dnaX_1	CLPUN_45350	CLPUN_07560	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.832
OOM73512.1	dnaX_2	CLPUN_45350	CLPUN_08590	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	DNA polymerase III subunit tau.	0.853
OOM73512.1	ssb	CLPUN_45350	CLPUN_05210	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	Single-stranded DNA-binding protein.	0.450
OOM73512.1	ssbA_2	CLPUN_45350	CLPUN_49970	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	Single-stranded DNA-binding protein A.	0.462
OOM74299.1	OOM73512.1	CLPUN_40040	CLPUN_45350	DNA polymerase III subunit epsilon.	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	0.898
OOM74299.1	OOM74555.1	CLPUN_40040	CLPUN_37960	DNA polymerase III subunit epsilon.	DNA polymerase III subunit beta.	0.907
OOM74299.1	OOM75059.1	CLPUN_40040	CLPUN_34960	DNA polymerase III subunit epsilon.	DNA polymerase III subunit delta.	0.954
OOM74299.1	dnaE	CLPUN_40040	CLPUN_14920	DNA polymerase III subunit epsilon.	DNA polymerase III subunit alpha.	0.966
OOM74299.1	dnaN	CLPUN_40040	CLPUN_48940	DNA polymerase III subunit epsilon.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.947
OOM74299.1	dnaX_1	CLPUN_40040	CLPUN_07560	DNA polymerase III subunit epsilon.	DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.943
OOM74299.1	dnaX_2	CLPUN_40040	CLPUN_08590	DNA polymerase III subunit epsilon.	DNA polymerase III subunit tau.	0.958
OOM74299.1	ssbA_2	CLPUN_40040	CLPUN_49970	DNA polymerase III subunit epsilon.	Single-stranded DNA-binding protein A.	0.407
OOM74555.1	OOM73512.1	CLPUN_37960	CLPUN_45350	DNA polymerase III subunit beta.	Hypothetical protein; Probable ATP-dependent helicase DinG homolog.	0.926
OOM74555.1	OOM74299.1	CLPUN_37960	CLPUN_40040	DNA polymerase III subunit beta.	DNA polymerase III subunit epsilon.	0.907
OOM74555.1	OOM75059.1	CLPUN_37960	CLPUN_34960	DNA polymerase III subunit beta.	DNA polymerase III subunit delta.	0.963