Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
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Co-expression
Experiments
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[Homology]
Score
thrB_3Homoserine kinase. (325 aa)    
Predicted Functional Partners:
yitJ
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase.
    
  0.753
metH
Methionine synthase.
    
  0.743
cdr_1
Coenzyme A disulfide reductase.
  
 
  0.610
cdr_2
Coenzyme A disulfide reductase.
  
 
  0.610
thrC
Threonine synthase.
    
 0.522
hom
Homoserine dehydrogenase.
    
 0.519
puuE_1
4-aminobutyrate aminotransferase PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
  0.512
dat_1
Diaminobutyrate--2-oxoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
  0.510
puuE_2
4-aminobutyrate aminotransferase PuuE.
 
  
  0.495
davT
5-aminovalerate aminotransferase DavT.
 
  
  0.495
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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