corC_2 protein (Clostridium puniceum) - STRING interaction network

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corC_2

Magnesium and cobalt efflux protein CorC. (436 aa)

Predicted Functional Partners:

guaA

0.910

purA

0.569

purH

0.553

rdgB

0.538

yfkN

0.536

xpt

0.532

ybeY

0.515

guaB_1

0.510

guaB_3

0.510

hpt_1

0.503

Your Current Organism:

Clostridium puniceum

NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
corC_2	guaA	CLPUN_32030	CLPUN_21520	Magnesium and cobalt efflux protein CorC.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.910
corC_2	guaB_1	CLPUN_32030	CLPUN_00700	Magnesium and cobalt efflux protein CorC.	Inosine-5'-monophosphate dehydrogenase.	0.510
corC_2	guaB_3	CLPUN_32030	CLPUN_21530	Magnesium and cobalt efflux protein CorC.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.510
corC_2	hpt_1	CLPUN_32030	CLPUN_05300	Magnesium and cobalt efflux protein CorC.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.503
corC_2	purA	CLPUN_32030	CLPUN_50080	Magnesium and cobalt efflux protein CorC.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.569
corC_2	purH	CLPUN_32030	CLPUN_39560	Magnesium and cobalt efflux protein CorC.	Bifunctional purine biosynthesis protein PurH.	0.553
corC_2	rdgB	CLPUN_32030	CLPUN_09900	Magnesium and cobalt efflux protein CorC.	dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.538
corC_2	xpt	CLPUN_32030	CLPUN_19980	Magnesium and cobalt efflux protein CorC.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.532
corC_2	ybeY	CLPUN_32030	CLPUN_35270	Magnesium and cobalt efflux protein CorC.	Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.515
corC_2	yfkN	CLPUN_32030	CLPUN_35830	Magnesium and cobalt efflux protein CorC.	Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family.	0.536
guaA	corC_2	CLPUN_21520	CLPUN_32030	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Magnesium and cobalt efflux protein CorC.	0.910
guaA	guaB_1	CLPUN_21520	CLPUN_00700	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase.	0.999
guaA	guaB_3	CLPUN_21520	CLPUN_21530	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	hpt_1	CLPUN_21520	CLPUN_05300	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.925
guaA	purA	CLPUN_21520	CLPUN_50080	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.962
guaA	purH	CLPUN_21520	CLPUN_39560	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional purine biosynthesis protein PurH.	0.956
guaA	rdgB	CLPUN_21520	CLPUN_09900	GMP synthase; Catalyzes the synthesis of GMP from XMP.	dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.960
guaA	xpt	CLPUN_21520	CLPUN_19980	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.967
guaA	yfkN	CLPUN_21520	CLPUN_35830	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family.	0.839
guaB_1	corC_2	CLPUN_00700	CLPUN_32030	Inosine-5'-monophosphate dehydrogenase.	Magnesium and cobalt efflux protein CorC.	0.510