Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spoIIAAAnti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. (111 aa)    
Predicted Functional Partners:
spoIIAB_2
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.998
sigF_1
RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.980
spoIIAB_1
Anti-sigma F factor.
  
 
 0.877
OOM75054.1
SpoVA protein.
 
   
 0.835
sigK_3
RNA polymerase sigma-28 factor precursor; Belongs to the sigma-70 factor family.
 
  
 0.817
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.803
spoIIE
Stage II sporulation protein E.
  
  
 0.788
spoVAD_2
Stage V sporulation protein AD.
 
   
 0.784
OOM75062.1
Stage II sporulation protein SpoIIP.
  
   
 0.780
OOM71120.1
Stage II sporulation protein SpoIIR.
  
   
 0.779
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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