Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppdKPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (877 aa)    
Predicted Functional Partners:
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
    
 0.928
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
    
 0.928
grsB_3
Gramicidin S synthase 2.
  
 
 0.920
accB_2
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.907
cfiB_1
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.884
pyk_1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.878
pyk_2
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.878
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
 
  
 0.867
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.863
pflB
Formate acetyltransferase.
    
 0.850
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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