Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sigK_3RNA polymerase sigma-28 factor precursor; Belongs to the sigma-70 factor family. (308 aa)    
Predicted Functional Partners:
spoIIAB_2
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.956
OOM77915.1
Anti-sigma-28 factor, FlgM.
  
 0.939
flhB_1
Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
  
  
 0.870
spoIIID_1
Stage III sporulation protein D.
 
   
 0.861
spoIIAB_1
Anti-sigma F factor.
  
 
 0.828
spoIIAA
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.817
spoVAD_2
Stage V sporulation protein AD.
 
    0.776
spoIVA
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.775
fliN
Flagellar motor switch protein FliN.
  
  
 0.774
spoIVB
SpoIVB peptidase precursor.
  
  
 0.772
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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