Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pyrK_3Dihydroorotate dehydrogenase B, electron transfer subunit. (296 aa)    
Predicted Functional Partners:
gltD_4
Glutamate synthase [NADPH] small chain.
 
 0.998
gltD_1
Glutamate synthase [NADPH] small chain.
 
 0.992
preA
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA.
  
 0.989
gltD_5
Glutamate synthase [NADPH] small chain.
 
 0.970
gltD_3
Glutamate synthase [NADPH] small chain.
 
 0.968
pyrD
Dihydroorotate dehydrogenase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 
 0.959
gltD_2
Glutamate synthase [NADPH] small chain.
 
 0.922
nifJ_1
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.902
nifJ_2
Pyruvate-flavodoxin oxidoreductase.
  
 
 0.902
sfrB_2
NADPH-Fe(3+) oxidoreductase subunit beta.
 
 
 0.868
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
Server load: low (20%) [HD]