Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rtpR_1Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase. (576 aa)    
Predicted Functional Partners:
rtpR_2
Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase.
     0.994
queE_1
7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.838
ycdT_1
Putative diguanylate cyclase YcdT.
     
  0.776
gmr_3
Cyclic di-GMP phosphodiesterase Gmr.
  
 
  0.768
OOM75109.1
Putative GTP cyclohydrolase 1 type 2.
     
  0.762
cqsS_1
CAI-1 autoinducer sensor kinase/phosphatase CqsS.
  
 
  0.761
ribBA_1
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.732
ribBA_2
Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.732
rsbP
Phosphoserine phosphatase RsbP.
  
 
  0.729
rpfG_3
Cyclic di-GMP phosphodiesterase response regulator RpfG.
  
 
  0.729
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
Server load: low (14%) [HD]