| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folE | gmr_4 | CLPUN_22900 | CLPUN_42940 | GTP cyclohydrolase 1. | Cyclic di-GMP phosphodiesterase Gmr. | 0.461 |
| folE | ndk | CLPUN_22900 | CLPUN_38990 | GTP cyclohydrolase 1. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.834 |
| folE | ribBA_1 | CLPUN_22900 | CLPUN_43980 | GTP cyclohydrolase 1. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.892 |
| folE | ribD_1 | CLPUN_22900 | CLPUN_44000 | GTP cyclohydrolase 1. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.628 |
| folE | ribD_2 | CLPUN_22900 | CLPUN_47970 | GTP cyclohydrolase 1. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.891 |
| folE | ribE_1 | CLPUN_22900 | CLPUN_43990 | GTP cyclohydrolase 1. | Riboflavin synthase. | 0.578 |
| folE | ribE_2 | CLPUN_22900 | CLPUN_47980 | GTP cyclohydrolase 1. | Riboflavin synthase. | 0.578 |
| folE | ribH_1 | CLPUN_22900 | CLPUN_43970 | GTP cyclohydrolase 1. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.549 |
| folE | ribH_2 | CLPUN_22900 | CLPUN_48000 | GTP cyclohydrolase 1. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.549 |
| folE | sulD | CLPUN_22900 | CLPUN_01760 | GTP cyclohydrolase 1. | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| gmr_4 | folE | CLPUN_42940 | CLPUN_22900 | Cyclic di-GMP phosphodiesterase Gmr. | GTP cyclohydrolase 1. | 0.461 |
| gmr_4 | ndk | CLPUN_42940 | CLPUN_38990 | Cyclic di-GMP phosphodiesterase Gmr. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.448 |
| gmr_4 | ribBA_1 | CLPUN_42940 | CLPUN_43980 | Cyclic di-GMP phosphodiesterase Gmr. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.906 |
| gmr_4 | ribD_2 | CLPUN_42940 | CLPUN_47970 | Cyclic di-GMP phosphodiesterase Gmr. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.584 |
| gmr_4 | sulD | CLPUN_42940 | CLPUN_01760 | Cyclic di-GMP phosphodiesterase Gmr. | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.411 |
| ndk | folE | CLPUN_38990 | CLPUN_22900 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP cyclohydrolase 1. | 0.834 |
| ndk | gmr_4 | CLPUN_38990 | CLPUN_42940 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Cyclic di-GMP phosphodiesterase Gmr. | 0.448 |
| ndk | ribBA_1 | CLPUN_38990 | CLPUN_43980 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.899 |
| ndk | ribD_1 | CLPUN_38990 | CLPUN_44000 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.611 |
| ndk | ribD_2 | CLPUN_38990 | CLPUN_47970 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.809 |
