Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rlmA23S rRNA (guanine(745)-N(1))-methyltransferase. (288 aa)    
Predicted Functional Partners:
grsB_3
Gramicidin S synthase 2.
    
 0.897
OOM80987.1
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.792
mbtB_1
Phenyloxazoline synthase MbtB.
     
 0.757
dhbF
Dimodular nonribosomal peptide synthase.
     
 0.755
puuB
Gamma-glutamylputrescine oxidoreductase.
   
 0.704
spsB
Signal peptidase IB; Belongs to the peptidase S26 family.
  
    0.701
gshAB
Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
 
 
 0.669
bioB
Biotin synthase.
  
 
 0.656
hndC_2
NADP-reducing hydrogenase subunit HndC.
    
 0.636
tycC_2
Tyrocidine synthase 3.
    
 0.609
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
Server load: low (14%) [HD]