Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
trxA_2Thioredoxin; Belongs to the thioredoxin family. (102 aa)    
Predicted Functional Partners:
trxB_5
Thioredoxin reductase.
 
 0.963
trxB_2
Thioredoxin reductase.
 
 0.905
nrdE2
Ribonucleoside-diphosphate reductase subunit alpha 2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.893
trxB_1
Thioredoxin reductase.
 
 0.869
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.864
OOM79309.1
NADH oxidase.
  
 0.806
trxB_3
Thioredoxin reductase.
  
 0.789
trxB_4
Thioredoxin reductase.
  
 0.789
gltB_1
Ferredoxin-dependent glutamate synthase 1.
   
 
 0.777
preA
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA.
  
 0.775
Your Current Organism:
Clostridium puniceum
NCBI taxonomy Id: 29367
Other names: ATCC 43978, C. puniceum, DSM 2619, ICMP 12529, NCIB 11596, NCIB:11596, NCIMB 11596, strain BL 70/20
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