| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| preA | pyrE | CLPUN_24620 | CLPUN_40210 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.973 |
| preA | pyrF | CLPUN_24620 | CLPUN_40240 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.948 |
| preA | pyrR | CLPUN_24620 | CLPUN_11830 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.945 |
| preA | udk_1 | CLPUN_24620 | CLPUN_19830 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Uridine kinase. | 0.597 |
| preA | udk_2 | CLPUN_24620 | CLPUN_25780 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Uridine kinase. | 0.658 |
| preA | udk_4 | CLPUN_24620 | CLPUN_28880 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Uridine kinase. | 0.597 |
| preA | upp | CLPUN_24620 | CLPUN_50540 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.872 |
| preA | yfkN | CLPUN_24620 | CLPUN_35830 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.590 |
| preA | ywlF | CLPUN_24620 | CLPUN_50550 | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | Putative sugar phosphate isomerase YwlF. | 0.437 |
| pyrE | preA | CLPUN_40210 | CLPUN_24620 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.973 |
| pyrE | pyrF | CLPUN_40210 | CLPUN_40240 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.999 |
| pyrE | pyrH | CLPUN_40210 | CLPUN_47680 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.779 |
| pyrE | pyrR | CLPUN_40210 | CLPUN_11830 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.967 |
| pyrE | udk_1 | CLPUN_40210 | CLPUN_19830 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Uridine kinase. | 0.599 |
| pyrE | udk_2 | CLPUN_40210 | CLPUN_25780 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Uridine kinase. | 0.889 |
| pyrE | udk_4 | CLPUN_40210 | CLPUN_28880 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Uridine kinase. | 0.599 |
| pyrE | upp | CLPUN_40210 | CLPUN_50540 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.825 |
| pyrE | yfkN | CLPUN_40210 | CLPUN_35830 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.670 |
| pyrF | preA | CLPUN_40240 | CLPUN_24620 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | NAD-dependent dihydropyrimidine dehydrogenase subunit PreA. | 0.948 |
| pyrF | pyrE | CLPUN_40240 | CLPUN_40210 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |