STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_1217PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sth:STH2778 hypothetical protein. (239 aa)    
Predicted Functional Partners:
Amet_1540
PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: fnu:FN0673 EbsC protein.
      0.769
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.553
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.519
Amet_1218
PFAM: Domain of unknown function DUF1893; KEGG: bfr:BF4297 putative TonB-dependent outer membrane receptor.
       0.476
Amet_3538
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: cth:Cthe_1079 nucleotidyl transferase.
  
  
 0.472
Amet_1216
PFAM: AzlC family protein; KEGG: oih:OB1119 branched-chain amino acid transporter.
       0.461
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.456
Amet_1215
PFAM: branched-chain amino acid transport; KEGG: oih:OB1120 hypothetical protein.
       0.445
Amet_2864
KEGG: tte:TTE1626 hypothetical protein.
  
     0.431
Amet_4751
2-alkenal reductase; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: tte:TTE2683 trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain.
  
 
 0.413
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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