STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_1422PFAM: pentapeptide repeat protein; KEGG: cac:CAC0073 uncharacterized protein, ortholog of YYBG B.subtilis. (298 aa)    
Predicted Functional Partners:
Amet_1423
PFAM: GCN5-related N-acetyltransferase; KEGG: bld:BLi00525 YdaF.
  
    0.721
Amet_1544
PFAM: Abortive infection protein; KEGG: bam:Bamb_3325 hypothetical protein.
  
     0.599
Amet_3917
PFAM: transcriptional regulator PadR family protein; KEGG: dsy:DSY0556 hypothetical protein.
 
     0.594
Amet_1908
PFAM: regulatory protein, TetR; KEGG: sth:STH2336 putative transcriptional regulator.
  
     0.582
Amet_1647
KEGG: tfu:Tfu_0754 putative ATP-binding protein.
  
     0.560
Amet_1421
PFAM: ThiJ/PfpI domain protein; KEGG: smu:SMU.1682c conserved hypothetical protein; possible intracellular protease.
 
     0.491
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.472
Amet_3107
PFAM: DNA gyrase, subunit B domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II; KEGG: cth:Cthe_0305 DNA topoisomerase (ATP-hydrolyzing).
   
 
 0.472
Amet_2450
PFAM: SCP-like extracellular protein; KEGG: bcl:ABC2540 hypothetical protein.
  
     0.455
Amet_3430
PFAM: SCP-like extracellular protein; KEGG: sth:STH564 hypothetical protein.
  
     0.429
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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