Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Amet_1663TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: mla:Mlab_0849 hypothetical protein. (250 aa)    
Predicted Functional Partners:
Amet_1665
TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family; PFAM: CRISPR-associated protein TM1801; KEGG: bha:BH0339 hypothetical protein.
 
 
 
 0.994
Amet_1664
TIGRFAM: CRISPR-associated protein, Csd1 family; KEGG: bcl:ABC3595 hypothetical protein.
 
 
 
 0.992
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.961
Amet_1666
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.958
Amet_1662
TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; SMART: DEAD-like helicases-like; KEGG: mla:Mlab_0850 hypothetical protein.
 
   
 0.949
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.944
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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