STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_2474PFAM: sigma-70 region 2 domain protein; KEGG: cth:Cthe_1012 RNA polymerase, sigma 28 subunit; Belongs to the sigma-70 factor family. (149 aa)    
Predicted Functional Partners:
Amet_2480
PFAM: sigma-70 region 4 domain protein; KEGG: cth:Cthe_1012 RNA polymerase, sigma 28 subunit.
 
     0.964
Amet_2512
TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: peptidase S55, SpoIVB; KEGG: tte:TTE1303 sporulation protein IVB.
  
  
 0.842
Amet_0725
PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: swo:Swol_0190 putative anti-sigma-28 factor, FlgM.
  
 
 0.763
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.761
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.749
Amet_2854
Sporulation stage IV, protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.744
Amet_2513
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.734
Amet_2220
PFAM: Stage V sporulation AD family protein; KEGG: tte:TTE1320 spore formation protein spoVAD.
 
  
 0.702
Amet_2219
TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA protein; KEGG: tte:TTE1319 spore formation protein spoVAC.
 
   
 0.695
Amet_0162
TIGRFAM: transcriptional regulator, AbrB family; Sporulation stage V, protein T; PFAM: SpoVT/AbrB domain protein; KEGG: mta:Moth_0083 transcriptional regulator, AbrB family.
  
   
 0.687
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.