STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scpBPutative transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (190 aa)    
Predicted Functional Partners:
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: lme:LEUM_1293 cytidylate kinase.
  
 0.935
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.852
Amet_2529
Polynucleotide adenylyltransferase region; PFAM: CBS domain containing protein; phosphoesterase, RecJ domain protein; Polynucleotide adenylyltransferase region; KEGG: cth:Cthe_0684 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.820
Amet_2530
PFAM: peptidase M50; KEGG: tte:TTE1323 Zn-dependent protease.
       0.812
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.782
Amet_2640
Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: cth:Cthe_0693 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.692
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.670
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
    0.670
Amet_3672
Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: bce:BC4704 ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.634
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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