STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_2606KEGG: gfo:orf2459 hypothetical protein. (650 aa)    
Predicted Functional Partners:
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.964
Amet_2603
KEGG: lin:lin1754 hypothetical protein.
 
     0.912
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.862
Amet_2604
TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: lin:lin1755 hypothetical protein.
 
   
 0.788
Amet_2607
Hypothetical protein.
       0.773
Amet_2608
Hypothetical protein.
       0.773
Amet_2144
PFAM: sigma-70 region 4 domain protein; RNA polymerase, alpha subunit domain protein; KEGG: ppe:PEPE_0533 hypothetical protein.
 
   0.749
Amet_2605
Hypothetical protein.
       0.746
Amet_2609
Hypothetical protein.
       0.727
Amet_4695
TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: ctc:CTC02090 ATP-dependent DNA helicase recQ.
  
 0.709
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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