STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_2854Sporulation stage IV, protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
Amet_2492
TIGRFAM: Sporulation stage III, protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA.
  
  
 0.912
Amet_0364
TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; KEGG: cno:NT01CX_0524 stage III sporulation protein D.
  
  
 0.909
Amet_2513
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.883
Amet_0359
TIGRFAM: SpoIID/LytB domain protein; Sporulation stage II, protein D firmicutes; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_2616 SpoIID/LytB domain protein containing protein.
  
  
 0.877
Amet_4592
TIGRFAM: Sporulation stage II, protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R.
  
   
 0.877
Amet_2495
TIGRFAM: Sporulation stage III, protein AD; KEGG: cth:Cthe_0842 stage III sporulation protein AD.
  
    0.875
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.862
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.855
Amet_2498
TIGRFAM: Sporulation stage III, protein AG; KEGG: tte:TTE1289 stage III sporulation protein AG.
  
  
 0.852
Amet_3054
PFAM: Stage II sporulation P family protein; KEGG: tte:TTE0947 stage II sporulation protein P.
 
   
 0.852
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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