node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amet_0285 | Amet_0287 | Amet_0285 | Amet_0287 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | 0.969 |
Amet_0285 | Amet_4512 | Amet_0285 | Amet_4512 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: tte:TTE2327 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.891 |
Amet_0285 | dnaJ | Amet_0285 | Amet_3047 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.993 |
Amet_0285 | groL | Amet_0285 | Amet_0834 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.964 |
Amet_0285 | groS | Amet_0285 | Amet_0833 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.891 |
Amet_0285 | grpE | Amet_0285 | Amet_3049 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.986 |
Amet_0285 | hrcA | Amet_0285 | Amet_3050 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.918 |
Amet_0285 | htpG | Amet_0285 | Amet_0521 | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.967 |
Amet_0287 | Amet_0285 | Amet_0287 | Amet_0285 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | 2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: cno:NT01CX_1453 DNAk protein. | 0.969 |
Amet_0287 | Amet_3529 | Amet_0287 | Amet_3529 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Hypothetical protein. | 0.904 |
Amet_0287 | Amet_4512 | Amet_0287 | Amet_4512 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: tte:TTE2327 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.712 |
Amet_0287 | dnaK | Amet_0287 | Amet_3048 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.904 |
Amet_0287 | groL | Amet_0287 | Amet_0834 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.883 |
Amet_0287 | groS | Amet_0287 | Amet_0833 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.727 |
Amet_0287 | grpE | Amet_0287 | Amet_3049 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.847 |
Amet_0287 | hrcA | Amet_0287 | Amet_3050 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.677 |
Amet_0287 | htpG | Amet_0287 | Amet_0521 | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.920 |
Amet_3529 | Amet_0287 | Amet_3529 | Amet_0287 | Hypothetical protein. | PFAM: TPR repeat-containing protein; heat shock protein DnaJ domain protein; SEC-C motif domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cno:NT01CX_1455 TPR domain protein. | 0.904 |
Amet_3529 | Amet_4512 | Amet_3529 | Amet_4512 | Hypothetical protein. | PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: tte:TTE2327 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.820 |
Amet_3529 | dnaJ | Amet_3529 | Amet_3047 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.829 |