STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amet_3609PFAM: S-layer domain protein; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: efa:EF0062 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family. (729 aa)    
Predicted Functional Partners:
Amet_1732
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: ctc:CTC01995 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.
 
  
 
0.992
Amet_3610
5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bcl:ABC0966 nucleotidase; Belongs to the 5'-nucleotidase family.
 
  
 
0.958
Amet_0542
5'-Nucleotidase domain protein; PFAM: Peptidoglycan-binding LysM; metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: bld:BLi00814 similar to 2',3'-cyclic-nucleotide 2'-phosphodiesterase; RBL02320; Belongs to the 5'-nucleotidase family.
 
  
 
0.927
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.924
udk
TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: cno:NT01CX_2269 uridine kinase.
 
 
 0.924
tdk
PFAM: thymidine kinase; KEGG: tte:TTE0140 Thymidine kinase.
 
  
  0.916
cinA
TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: cac:CAC3586 competence-damage inducible protein, CINA; Belongs to the CinA family.
  
 
  0.916
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
  0.912
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.911
Amet_2652
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cth:Cthe_0741 adenylosuccinate lyase.
  
 
 0.910
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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