STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
Amet_4068
TIGRFAM: pyruvate kinase; PFAM: PEP-utilising protein, mobile region; Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; KEGG: tte:TTE1815 pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.999
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: btl:BALH_4440 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.994
Amet_3675
TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase, class-II; KEGG: cth:Cthe_0349 fructose-1,6-bisphosphate aldolase, class II.
 
 
 0.964
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
  
 0.960
fbp
PFAM: fructose-1,6-bisphosphatase; KEGG: cac:CAC1572 fructose-1,6-bisphosphatase.
  
  
 0.951
tal
Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.949
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.946
Amet_4648
TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; KEGG: ctc:CTC01332 transketolase; Belongs to the transketolase family.
  
 
 0.938
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.935
Amet_0322
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: chy:CHY_0787 fructose-1,6-bisphosphatase, class II.
  
 
 0.931
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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