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purA protein (Alkaliphilus metalliredigens) - STRING interaction network
"purA" - Adenylosuccinate synthetase in Alkaliphilus metalliredigens
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (427 aa)    
Predicted Functional Partners:
Amet_2652
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- cth-Cthe_0741 adenylosuccinate lyase (477 aa)
 
 
  0.992
purH
Bifunctional purine biosynthesis protein PurH; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region; KEGG- cth-Cthe_1246 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (508 aa)
 
  0.991
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (485 aa)
 
 
  0.991
Amet_2903
TIGRFAM- hypoxanthine phosphoribosyltransferase; PFAM- phosphoribosyltransferase; KEGG- tte-TTE2394 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family (179 aa)
   
 
  0.962
argG
PFAM- argininosuccinate synthase; KEGG- dsy-DSY0785 hypothetical protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily (414 aa)
   
 
  0.958
pyrB
TIGRFAM- aspartate carbamoyltransferase; PFAM- aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; KEGG- cpf-CPF_1387 aspartate carbamoyltransferase; Belongs to the ATCase/OTCase family (311 aa)
   
 
  0.957
Amet_1621
TIGRFAM- hypoxanthine phosphoribosyltransferase; PFAM- phosphoribosyltransferase; KEGG- cno-NT01CX_1811 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family (179 aa)
   
 
  0.935
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (510 aa)
 
   
  0.935
Amet_3610
5’-Nucleotidase domain protein; PFAM- Peptidoglycan-binding LysM; metallophosphoesterase; 5’-Nucleotidase domain protein; KEGG- bcl-ABC0966 nucleotidase; Belongs to the 5’-nucleotidase family (596 aa)
     
  0.932
Amet_4405
TIGRFAM- asparagine synthase (glutamine-hydrolyzing); PFAM- glutamine amidotransferase, class-II; asparagine synthase; KEGG- cth-Cthe_0556 asparagine synthase (glutamine-hydrolyzing) (613 aa)
   
 
  0.917
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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