STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (111 aa)    
Predicted Functional Partners:
rpmH
PFAM: ribosomal protein L34; KEGG: cac:CAC3739 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.992
Amet_4800
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
  
 0.982
rex-2
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
    0.919
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
    0.917
Amet_4799
PFAM: 60 kDa inner membrane insertion protein; KEGG: mta:Moth_2521 60 kDa inner membrane insertion protein.
  
  
 0.917
Amet_4798
PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: cpe:CPE2656 SpoIIIJ-associated protein.
 
  
 0.908
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  
 0.887
rplD
Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
  
 0.885
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
    0.880
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
 
    0.871
Your Current Organism:
Alkaliphilus metalliredigens
NCBI taxonomy Id: 293826
Other names: A. metalliredigens QYMF, Alkaliphilus metalliredigens QYMF, Alkaliphilus metalliredigens str. QYMF, Alkaliphilus metalliredigens strain QYMF
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