Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folE2GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. (292 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.933
AMG19397.1
6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.928
queD
6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.914
AMG19667.1
Alkaline phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alkaline phosphatase family.
     
  0.900
moaA
Cyclic pyranopterin phosphate synthase MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.900
AMG18871.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.866
bshB2
Bacillithiol biosynthesis deacetylase BshB2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.847
nrdD
Anaerobic ribonucleoside triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
AMG20236.1
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.800
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 29385
Other names: ATCC 15305, BCRC 10786, CCM 883, CCRC 10786, CCRC:10786, CCUG 3706, CIP 76.125, DSM 20229, IAM 12452, JCM 2427, LMG 13350, LMG:13350, NBRC 102446, NCAIM B.01067, NCCB 73011, NCIB 8711, NCIB:8711, NCTC 7292, NRRL B-14751, S. saprophyticus, Staphylococcus sp. HAR3
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