| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMG20398.1 | dnaI | AL528_09385 | AL528_08345 | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| AMG20398.1 | rpoE | AL528_09385 | AL528_06230 | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.664 |
| AMG20398.1 | yaaA | AL528_09385 | AL528_02480 | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.609 |
| AMG20398.1 | yabA | AL528_09385 | AL528_01530 | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA replication protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.470 |
| AMG20398.1 | yqeH | AL528_09385 | AL528_08725 | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome biogenesis GTPase YqeH; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
| dnaI | AMG20398.1 | AL528_08345 | AL528_09385 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| dnaI | dnaN | AL528_08345 | AL528_02475 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.489 |
| dnaI | rpoE | AL528_08345 | AL528_06230 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.681 |
| dnaI | yaaA | AL528_08345 | AL528_02480 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.580 |
| dnaI | yqeH | AL528_08345 | AL528_08725 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome biogenesis GTPase YqeH; In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.531 |
| dnaN | dnaI | AL528_02475 | AL528_08345 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.489 |
| dnaN | gltB | AL528_02475 | AL528_01630 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| dnaN | gyrB | AL528_02475 | AL528_02490 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.532 |
| dnaN | recF | AL528_02475 | AL528_02485 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.831 |
| dnaN | yaaA | AL528_02475 | AL528_02480 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.625 |
| dnaN | yabA | AL528_02475 | AL528_01530 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA replication protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family. | 0.709 |
| gltB | dnaN | AL528_01630 | AL528_02475 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.442 |
| gltB | gyrB | AL528_01630 | AL528_02490 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.570 |
| gltB | recF | AL528_01630 | AL528_02485 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.495 |
| gltB | yaaA | AL528_01630 | AL528_02480 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.585 |
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