close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMG19427.13-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (427 aa)    
Predicted Functional Partners:
AMG19425.1
hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
mvk
Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
AMG19426.1
3-ketoacyl-CoA thiolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.897
mvaD
Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.851
fni
Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.845
AMG18847.1
Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.743
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
   
 
 0.659
AMG19428.1
Lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.557
AMG20354.1
Glucohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.507
AMG19236.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
  
 0.501
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 29385
Other names: ATCC 15305, BCRC 10786, CCM 883, CCRC 10786, CCRC:10786, CCUG 3706, CIP 76.125, DSM 20229, IAM 12452, JCM 2427, LMG 13350, LMG:13350, NBRC 102446, NCAIM B.01067, NCCB 73011, NCIB 8711, NCIB:8711, NCTC 7292, NRRL B-14751, S. saprophyticus, Staphylococcus sp. HAR3
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.