Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lrgAMurein hydrolase transporter LrgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)    
Predicted Functional Partners:
lrgB
Antiholin LrgB; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
  
 0.995
AMG19543.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.952
AMG19432.1
Holin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.950
AMG19544.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.919
tarJ
Ribitol-5-phosphate dehydrogenase; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate; Belongs to the zinc-containing alcohol dehydrogenase family.
      
 0.541
AMG19540.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.433
tarI
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate.
      
 0.414
Your Current Organism:
Staphylococcus saprophyticus
NCBI taxonomy Id: 29385
Other names: ATCC 15305, BCRC 10786, CCM 883, CCRC 10786, CCRC:10786, CCUG 3706, CIP 76.125, DSM 20229, IAM 12452, JCM 2427, LMG 13350, LMG:13350, NBRC 102446, NCAIM B.01067, NCCB 73011, NCIB 8711, NCIB:8711, NCTC 7292, NRRL B-14751, S. saprophyticus, Staphylococcus sp. HAR3
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