| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMG18837.1 | AMG19784.1 | AL528_00665 | AL528_05965 | Vitamin B12 ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.579 |
| AMG18846.1 | AMG19784.1 | AL528_00710 | AL528_05965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0741 family. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.447 |
| AMG18851.1 | AMG19784.1 | AL528_00740 | AL528_05965 | Heme-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.934 |
| AMG18851.1 | ctaB | AL528_00740 | AL528_11305 | Heme-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.929 |
| AMG18851.1 | hemH | AL528_00740 | AL528_07410 | Heme-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.987 |
| AMG19464.1 | AMG19784.1 | AL528_04265 | AL528_05965 | Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.438 |
| AMG19617.1 | AMG19784.1 | AL528_05110 | AL528_05965 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.464 |
| AMG19784.1 | AMG18837.1 | AL528_05965 | AL528_00665 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Vitamin B12 ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.579 |
| AMG19784.1 | AMG18846.1 | AL528_05965 | AL528_00710 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0741 family. | 0.447 |
| AMG19784.1 | AMG18851.1 | AL528_05965 | AL528_00740 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Heme-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| AMG19784.1 | AMG19464.1 | AL528_05965 | AL528_04265 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| AMG19784.1 | AMG19617.1 | AL528_05965 | AL528_05110 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.464 |
| AMG19784.1 | AMG19785.1 | AL528_05965 | AL528_05970 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| AMG19784.1 | AMG20826.1 | AL528_05965 | AL528_11635 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.456 |
| AMG19784.1 | AMG20915.1 | AL528_05965 | AL528_12105 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.561 |
| AMG19784.1 | ctaB | AL528_05965 | AL528_11305 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Hypothetical protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. | 0.912 |
| AMG19784.1 | hemH | AL528_05965 | AL528_07410 | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.903 |
| AMG19785.1 | AMG19784.1 | AL528_05970 | AL528_05965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.528 |
| AMG20826.1 | AMG19784.1 | AL528_11635 | AL528_05965 | MarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.456 |
| AMG20915.1 | AMG19784.1 | AL528_12105 | AL528_05965 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heme-degrading monooxygenase IsdG; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron. | 0.561 |
