| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMG20419.1 | AMG20420.1 | AL528_09500 | AL528_09505 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
| AMG20419.1 | AMG20422.1 | AL528_09500 | AL528_09515 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.722 |
| AMG20419.1 | AMG20423.1 | AL528_09500 | AL528_09520 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.709 |
| AMG20419.1 | AMG20424.1 | AL528_09500 | AL528_09525 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. | 0.699 |
| AMG20419.1 | AMG20425.1 | AL528_09500 | AL528_09530 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | 0.619 |
| AMG20419.1 | AMG20426.1 | AL528_09500 | AL528_09535 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |
| AMG20419.1 | AMG20428.1 | AL528_09500 | AL528_09545 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phosphatidic acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.592 |
| AMG20419.1 | msrA-2 | AL528_09500 | AL528_09510 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.858 |
| AMG20419.1 | murG | AL528_09500 | AL528_09540 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.606 |
| AMG20419.1 | thyA | AL528_09500 | AL528_09495 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| AMG20420.1 | AMG20419.1 | AL528_09505 | AL528_09500 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.888 |
| AMG20420.1 | AMG20422.1 | AL528_09505 | AL528_09515 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.716 |
| AMG20420.1 | AMG20423.1 | AL528_09505 | AL528_09520 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.704 |
| AMG20420.1 | AMG20424.1 | AL528_09505 | AL528_09525 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0346 family. | 0.704 |
| AMG20420.1 | AMG20425.1 | AL528_09505 | AL528_09530 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | 0.622 |
| AMG20420.1 | AMG20426.1 | AL528_09505 | AL528_09535 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.611 |
| AMG20420.1 | AMG20428.1 | AL528_09505 | AL528_09545 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphatidic acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.599 |
| AMG20420.1 | msrA-2 | AL528_09505 | AL528_09510 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.716 |
| AMG20420.1 | murG | AL528_09505 | AL528_09540 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.608 |
| AMG20420.1 | thyA | AL528_09505 | AL528_09495 | Fatty acid-binding protein DegV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.740 |