| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL26955.1 | metQ_2 | SRM1_00278 | SRM1_00280 | Alpha/beta hydrolase family protein. | Methionine-binding lipoprotein MetQ precursor. | 0.433 |
| CEL26955.1 | prpR | SRM1_00278 | SRM1_00279 | Alpha/beta hydrolase family protein. | Propionate catabolism operon regulatory protein. | 0.658 |
| cysNC | metF | SRM1_00926 | SRM1_05375 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.461 |
| cysNC | metK | SRM1_00926 | SRM1_05360 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.405 |
| cysNC | metQ_2 | SRM1_00926 | SRM1_00280 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Methionine-binding lipoprotein MetQ precursor. | 0.415 |
| metF | cysNC | SRM1_05375 | SRM1_00926 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.461 |
| metF | metI | SRM1_05375 | SRM1_00289 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | D-methionine transport system permease protein MetI. | 0.400 |
| metF | metK | SRM1_05375 | SRM1_05360 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.842 |
| metF | metN_1 | SRM1_05375 | SRM1_00124 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.474 |
| metF | metN_2 | SRM1_05375 | SRM1_00290 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.474 |
| metF | metP | SRM1_05375 | SRM1_00125 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine import system permease protein MetP. | 0.580 |
| metF | metQ_2 | SRM1_05375 | SRM1_00280 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine-binding lipoprotein MetQ precursor. | 0.405 |
| metI | metF | SRM1_00289 | SRM1_05375 | D-methionine transport system permease protein MetI. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.400 |
| metI | metN_1 | SRM1_00289 | SRM1_00124 | D-methionine transport system permease protein MetI. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.979 |
| metI | metN_2 | SRM1_00289 | SRM1_00290 | D-methionine transport system permease protein MetI. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.995 |
| metI | metQ_2 | SRM1_00289 | SRM1_00280 | D-methionine transport system permease protein MetI. | Methionine-binding lipoprotein MetQ precursor. | 0.994 |
| metK | cysNC | SRM1_05360 | SRM1_00926 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.405 |
| metK | metF | SRM1_05360 | SRM1_05375 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.842 |
| metK | metN_1 | SRM1_05360 | SRM1_00124 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.496 |
| metK | metN_2 | SRM1_05360 | SRM1_00290 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.496 |