| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gltB | guaA_2 | SRM1_00466 | SRM1_04632 | Glutamate synthase [NADPH] large chain precursor. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.855 |
| gltB | thiI | SRM1_00466 | SRM1_00398 | Glutamate synthase [NADPH] large chain precursor. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.675 |
| gltB | typA | SRM1_00466 | SRM1_00399 | Glutamate synthase [NADPH] large chain precursor. | GTP-binding protein TypA/BipA. | 0.767 |
| guaA_2 | gltB | SRM1_04632 | SRM1_00466 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Glutamate synthase [NADPH] large chain precursor. | 0.855 |
| guaA_2 | infC | SRM1_04632 | SRM1_02090 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 0.477 |
| guaA_2 | rplA | SRM1_04632 | SRM1_05189 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.977 |
| guaA_2 | rpsI | SRM1_04632 | SRM1_04741 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.540 |
| guaA_2 | thiI | SRM1_04632 | SRM1_00398 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.658 |
| guaA_2 | typA | SRM1_04632 | SRM1_00399 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | GTP-binding protein TypA/BipA. | 0.708 |
| guaA_2 | ychF | SRM1_04632 | SRM1_04808 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.796 |
| infC | guaA_2 | SRM1_02090 | SRM1_04632 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.477 |
| infC | rplA | SRM1_02090 | SRM1_05189 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.916 |
| infC | rpsI | SRM1_02090 | SRM1_04741 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.957 |
| infC | typA | SRM1_02090 | SRM1_00399 | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. | GTP-binding protein TypA/BipA. | 0.652 |
| rhlB | rplA | SRM1_01013 | SRM1_05189 | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.541 |
| rhlB | typA | SRM1_01013 | SRM1_00399 | ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. | GTP-binding protein TypA/BipA. | 0.632 |
| rhlE_2 | rplA | SRM1_04965 | SRM1_05189 | ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.541 |
| rhlE_2 | typA | SRM1_04965 | SRM1_00399 | ATP-dependent RNA helicase RhlE; Belongs to the DEAD box helicase family. | GTP-binding protein TypA/BipA. | 0.622 |
| rhlE_3 | rplA | SRM1_05377 | SRM1_05189 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.541 |
| rhlE_3 | typA | SRM1_05377 | SRM1_00399 | ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. | GTP-binding protein TypA/BipA. | 0.625 |