| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiC_1 | hflC_1 | SRM1_00579 | SRM1_00585 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | 0.565 |
| amiC_1 | hflK_2 | SRM1_00579 | SRM1_00584 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease. | 0.568 |
| amiC_1 | hflX | SRM1_00579 | SRM1_00583 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.748 |
| amiC_1 | hfq | SRM1_00579 | SRM1_00582 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.746 |
| amiC_1 | miaA | SRM1_00579 | SRM1_00581 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.903 |
| amiC_1 | mutL | SRM1_00579 | SRM1_00580 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.905 |
| amiC_1 | nnr | SRM1_00579 | SRM1_00577 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.931 |
| amiC_1 | tsaE | SRM1_00579 | SRM1_00578 | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.909 |
| hflC_1 | amiC_1 | SRM1_00585 | SRM1_00579 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | 0.565 |
| hflC_1 | hflK_2 | SRM1_00585 | SRM1_00584 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease. | 0.997 |
| hflC_1 | hflX | SRM1_00585 | SRM1_00583 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.754 |
| hflC_1 | hfq | SRM1_00585 | SRM1_00582 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.881 |
| hflC_1 | miaA | SRM1_00585 | SRM1_00581 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.749 |
| hflC_1 | mutL | SRM1_00585 | SRM1_00580 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.445 |
| hflC_1 | nnr | SRM1_00585 | SRM1_00577 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.596 |
| hflC_1 | rlmE | SRM1_00585 | SRM1_00817 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.419 |
| hflC_1 | tsaE | SRM1_00585 | SRM1_00578 | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE. | 0.476 |
| hflK_2 | amiC_1 | SRM1_00584 | SRM1_00579 | Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease. | N-acetylmuramoyl-L-alanine amidase AmiC precursor. | 0.568 |
| hflK_2 | hflC_1 | SRM1_00584 | SRM1_00585 | Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease. | Modulator of FtsH protease HflC; HflC and HflK could regulate a protease. | 0.997 |
| hflK_2 | hflX | SRM1_00584 | SRM1_00583 | Modulator of FtsH protease HflK; HflC and HflK could encode or regulate a protease. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.775 |