| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL27336.1 | CEL29591.1 | SRM1_00663 | SRM1_02945 | cobalt-precorrin-6A synthase. | Cobalamin biosynthesis protein CbiG. | 0.991 |
| CEL27336.1 | cobB_1 | SRM1_00663 | SRM1_01639 | cobalt-precorrin-6A synthase. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.903 |
| CEL27336.1 | cobH | SRM1_00663 | SRM1_00665 | cobalt-precorrin-6A synthase. | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | 0.923 |
| CEL27336.1 | cobI | SRM1_00663 | SRM1_00666 | cobalt-precorrin-6A synthase. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.963 |
| CEL27336.1 | cobJ | SRM1_00663 | SRM1_00667 | cobalt-precorrin-6A synthase. | Precorrin-3B C(17)-methyltransferase. | 0.999 |
| CEL27336.1 | cobK | SRM1_00663 | SRM1_00662 | cobalt-precorrin-6A synthase. | Precorrin-6A reductase. | 0.999 |
| CEL27336.1 | cobL | SRM1_00663 | SRM1_00664 | cobalt-precorrin-6A synthase. | Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]. | 0.998 |
| CEL27336.1 | cobM | SRM1_00663 | SRM1_02946 | cobalt-precorrin-6A synthase. | Precorrin-4 C(11)-methyltransferase. | 0.970 |
| CEL27336.1 | cobQ | SRM1_00663 | SRM1_01643 | cobalt-precorrin-6A synthase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.915 |
| CEL27336.1 | cysG | SRM1_00663 | SRM1_03423 | cobalt-precorrin-6A synthase. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.837 |
| CEL29591.1 | CEL27336.1 | SRM1_02945 | SRM1_00663 | Cobalamin biosynthesis protein CbiG. | cobalt-precorrin-6A synthase. | 0.991 |
| CEL29591.1 | cobB_1 | SRM1_02945 | SRM1_01639 | Cobalamin biosynthesis protein CbiG. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.839 |
| CEL29591.1 | cobH | SRM1_02945 | SRM1_00665 | Cobalamin biosynthesis protein CbiG. | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | 0.532 |
| CEL29591.1 | cobI | SRM1_02945 | SRM1_00666 | Cobalamin biosynthesis protein CbiG. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.810 |
| CEL29591.1 | cobJ | SRM1_02945 | SRM1_00667 | Cobalamin biosynthesis protein CbiG. | Precorrin-3B C(17)-methyltransferase. | 0.995 |
| CEL29591.1 | cobK | SRM1_02945 | SRM1_00662 | Cobalamin biosynthesis protein CbiG. | Precorrin-6A reductase. | 0.840 |
| CEL29591.1 | cobL | SRM1_02945 | SRM1_00664 | Cobalamin biosynthesis protein CbiG. | Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]. | 0.940 |
| CEL29591.1 | cobM | SRM1_02945 | SRM1_02946 | Cobalamin biosynthesis protein CbiG. | Precorrin-4 C(11)-methyltransferase. | 0.999 |
| CEL29591.1 | cobQ | SRM1_02945 | SRM1_01643 | Cobalamin biosynthesis protein CbiG. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.767 |
| CEL29591.1 | cysG | SRM1_02945 | SRM1_03423 | Cobalamin biosynthesis protein CbiG. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.862 |