| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL27336.1 | cobB_1 | SRM1_00663 | SRM1_01639 | cobalt-precorrin-6A synthase. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.887 |
| CEL27336.1 | cobH | SRM1_00663 | SRM1_00665 | cobalt-precorrin-6A synthase. | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | 0.803 |
| CEL27336.1 | cobI | SRM1_00663 | SRM1_00666 | cobalt-precorrin-6A synthase. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.908 |
| CEL27336.1 | cobJ | SRM1_00663 | SRM1_00667 | cobalt-precorrin-6A synthase. | Precorrin-3B C(17)-methyltransferase. | 0.997 |
| CEL27336.1 | cobK | SRM1_00663 | SRM1_00662 | cobalt-precorrin-6A synthase. | Precorrin-6A reductase. | 0.988 |
| CEL27336.1 | cobL | SRM1_00663 | SRM1_00664 | cobalt-precorrin-6A synthase. | Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]. | 0.998 |
| CEL27336.1 | cobM | SRM1_00663 | SRM1_02946 | cobalt-precorrin-6A synthase. | Precorrin-4 C(11)-methyltransferase. | 0.942 |
| CEL27336.1 | cobQ | SRM1_00663 | SRM1_01643 | cobalt-precorrin-6A synthase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.905 |
| CEL27336.1 | cobS | SRM1_00663 | SRM1_01647 | cobalt-precorrin-6A synthase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.655 |
| CEL27336.1 | sumT_2 | SRM1_00663 | SRM1_03309 | cobalt-precorrin-6A synthase. | Uroporphyrinogen-III C-methyltransferase. | 0.550 |
| cobB_1 | CEL27336.1 | SRM1_01639 | SRM1_00663 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cobalt-precorrin-6A synthase. | 0.887 |
| cobB_1 | cobH | SRM1_01639 | SRM1_00665 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-8X methylmutase; Unknown EC_number=5.4.99.61. | 0.896 |
| cobB_1 | cobI | SRM1_01639 | SRM1_00666 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. | 0.868 |
| cobB_1 | cobJ | SRM1_01639 | SRM1_00667 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-3B C(17)-methyltransferase. | 0.961 |
| cobB_1 | cobK | SRM1_01639 | SRM1_00662 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6A reductase. | 0.864 |
| cobB_1 | cobL | SRM1_01639 | SRM1_00664 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-6Y C(5,15)-methyltransferase [decarboxylating]. | 0.912 |
| cobB_1 | cobM | SRM1_01639 | SRM1_02946 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase. | 0.896 |
| cobB_1 | cobQ | SRM1_01639 | SRM1_01643 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.995 |
| cobB_1 | cobS | SRM1_01639 | SRM1_01647 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.930 |
| cobB_1 | sumT_2 | SRM1_01639 | SRM1_03309 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Uroporphyrinogen-III C-methyltransferase. | 0.625 |