| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL27425.1 | acsA_1 | SRM1_00752 | SRM1_02739 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase. | 0.951 |
| CEL27425.1 | acsA_2 | SRM1_00752 | SRM1_04860 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.918 |
| CEL27425.1 | acs_2 | SRM1_00752 | SRM1_04240 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.955 |
| CEL27425.1 | bkdB | SRM1_00752 | SRM1_03245 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.957 |
| CEL27425.1 | mmsA_2 | SRM1_00752 | SRM1_00761 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Methylmalonate-semialdehyde dehydrogenase [acylating]. | 0.973 |
| CEL27425.1 | prpC | SRM1_00752 | SRM1_01852 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.956 |
| CEL27425.1 | pta | SRM1_00752 | SRM1_00928 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.960 |
| acsA_1 | CEL27425.1 | SRM1_02739 | SRM1_00752 | Acetyl-coenzyme A synthetase. | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.951 |
| acsA_1 | acsA_2 | SRM1_02739 | SRM1_04860 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.964 |
| acsA_1 | acs_2 | SRM1_02739 | SRM1_04240 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.965 |
| acsA_1 | bkdB | SRM1_02739 | SRM1_03245 | Acetyl-coenzyme A synthetase. | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.959 |
| acsA_1 | leuA | SRM1_02739 | SRM1_04638 | Acetyl-coenzyme A synthetase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.964 |
| acsA_1 | mmsA_2 | SRM1_02739 | SRM1_00761 | Acetyl-coenzyme A synthetase. | Methylmalonate-semialdehyde dehydrogenase [acylating]. | 0.963 |
| acsA_1 | mmsB | SRM1_02739 | SRM1_00762 | Acetyl-coenzyme A synthetase. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.461 |
| acsA_1 | prpC | SRM1_02739 | SRM1_01852 | Acetyl-coenzyme A synthetase. | 2-methylcitrate synthase; Belongs to the citrate synthase family. | 0.972 |
| acsA_1 | pta | SRM1_02739 | SRM1_00928 | Acetyl-coenzyme A synthetase. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.969 |
| acsA_1 | thlA_1 | SRM1_02739 | SRM1_02737 | Acetyl-coenzyme A synthetase. | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.991 |
| acsA_2 | CEL27425.1 | SRM1_04860 | SRM1_00752 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.918 |
| acsA_2 | acsA_1 | SRM1_04860 | SRM1_02739 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase. | 0.964 |
| acsA_2 | acs_2 | SRM1_04860 | SRM1_04240 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.954 |