| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL27474.1 | pasI | SRM1_00802 | SRM1_00804 | Sodium:neurotransmitter symporter family protein. | Persistence and stress-resistance antitoxin PasI; Belongs to the UPF0125 (RnfH) family. | 0.898 |
| CEL27474.1 | ratA | SRM1_00802 | SRM1_00803 | Sodium:neurotransmitter symporter family protein. | Ribosome association toxin RatA. | 0.936 |
| CEL27474.1 | smpB | SRM1_00802 | SRM1_00801 | Sodium:neurotransmitter symporter family protein. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.832 |
| coaBC | ctaA | SRM1_05679 | SRM1_00129 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Heme A synthase. | 0.772 |
| coaBC | ratA | SRM1_05679 | SRM1_00803 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ribosome association toxin RatA. | 0.727 |
| ctaA | coaBC | SRM1_00129 | SRM1_05679 | Heme A synthase. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.772 |
| ctaA | ratA | SRM1_00129 | SRM1_00803 | Heme A synthase. | Ribosome association toxin RatA. | 0.775 |
| dnaQ | ratA | SRM1_02231 | SRM1_00803 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ribosome association toxin RatA. | 0.659 |
| dnaQ | ubiG_2 | SRM1_02231 | SRM1_04028 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.566 |
| pasI | CEL27474.1 | SRM1_00804 | SRM1_00802 | Persistence and stress-resistance antitoxin PasI; Belongs to the UPF0125 (RnfH) family. | Sodium:neurotransmitter symporter family protein. | 0.898 |
| pasI | ratA | SRM1_00804 | SRM1_00803 | Persistence and stress-resistance antitoxin PasI; Belongs to the UPF0125 (RnfH) family. | Ribosome association toxin RatA. | 0.962 |
| pasI | smpB | SRM1_00804 | SRM1_00801 | Persistence and stress-resistance antitoxin PasI; Belongs to the UPF0125 (RnfH) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.838 |
| ratA | CEL27474.1 | SRM1_00803 | SRM1_00802 | Ribosome association toxin RatA. | Sodium:neurotransmitter symporter family protein. | 0.936 |
| ratA | coaBC | SRM1_00803 | SRM1_05679 | Ribosome association toxin RatA. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.727 |
| ratA | ctaA | SRM1_00803 | SRM1_00129 | Ribosome association toxin RatA. | Heme A synthase. | 0.775 |
| ratA | dnaQ | SRM1_00803 | SRM1_02231 | Ribosome association toxin RatA. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.659 |
| ratA | pasI | SRM1_00803 | SRM1_00804 | Ribosome association toxin RatA. | Persistence and stress-resistance antitoxin PasI; Belongs to the UPF0125 (RnfH) family. | 0.962 |
| ratA | smpB | SRM1_00803 | SRM1_00801 | Ribosome association toxin RatA. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.670 |
| ratA | ubiB_1 | SRM1_00803 | SRM1_00436 | Ribosome association toxin RatA. | Putative protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. | 0.741 |
| ratA | ubiB_2 | SRM1_00803 | SRM1_02373 | Ribosome association toxin RatA. | Putative protein kinase UbiB. | 0.659 |