| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL27501.1 | CEL27502.1 | SRM1_00831 | SRM1_00832 | Hypothetical protein. | Hypothetical protein. | 0.430 |
| CEL27501.1 | CEL29454.1 | SRM1_00831 | SRM1_02805 | Hypothetical protein. | 1-phosphatidylinositol phosphodiesterase precursor. | 0.421 |
| CEL27501.1 | acuC | SRM1_00831 | SRM1_04963 | Hypothetical protein. | Acetoin utilization protein AcuC. | 0.419 |
| CEL27501.1 | aphA | SRM1_00831 | SRM1_05777 | Hypothetical protein. | Acetylpolyamine aminohydrolase. | 0.419 |
| CEL27501.1 | gyrB | SRM1_00831 | SRM1_00059 | Hypothetical protein. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.493 |
| CEL27501.1 | parE | SRM1_00831 | SRM1_00552 | Hypothetical protein. | DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.493 |
| CEL27501.1 | polA | SRM1_00831 | SRM1_00115 | Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.497 |
| CEL27501.1 | recA | SRM1_00831 | SRM1_01189 | Hypothetical protein. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.405 |
| CEL27501.1 | scpA | SRM1_00831 | SRM1_01477 | Hypothetical protein. | Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.716 |
| CEL27501.1 | topA | SRM1_00831 | SRM1_03787 | Hypothetical protein. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.420 |
| CEL27502.1 | CEL27501.1 | SRM1_00832 | SRM1_00831 | Hypothetical protein. | Hypothetical protein. | 0.430 |
| CEL29454.1 | CEL27501.1 | SRM1_02805 | SRM1_00831 | 1-phosphatidylinositol phosphodiesterase precursor. | Hypothetical protein. | 0.421 |
| acuC | CEL27501.1 | SRM1_04963 | SRM1_00831 | Acetoin utilization protein AcuC. | Hypothetical protein. | 0.419 |
| acuC | aphA | SRM1_04963 | SRM1_05777 | Acetoin utilization protein AcuC. | Acetylpolyamine aminohydrolase. | 0.488 |
| aphA | CEL27501.1 | SRM1_05777 | SRM1_00831 | Acetylpolyamine aminohydrolase. | Hypothetical protein. | 0.419 |
| aphA | acuC | SRM1_05777 | SRM1_04963 | Acetylpolyamine aminohydrolase. | Acetoin utilization protein AcuC. | 0.488 |
| gyrB | CEL27501.1 | SRM1_00059 | SRM1_00831 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein. | 0.493 |
| gyrB | polA | SRM1_00059 | SRM1_00115 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.713 |
| gyrB | recA | SRM1_00059 | SRM1_01189 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.790 |
| gyrB | topA | SRM1_00059 | SRM1_03787 | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.503 |