| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cra | fruA | SRM1_00839 | SRM1_00842 | Catabolite repressor/activator. | PTS system fructose-specific EIIBC component. | 0.929 |
| cra | lacC | SRM1_00839 | SRM1_00841 | Catabolite repressor/activator. | Tagatose-6-phosphate kinase. | 0.931 |
| cra | ptsI_1 | SRM1_00839 | SRM1_00840 | Catabolite repressor/activator. | Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. | 0.977 |
| cra | ptsI_2 | SRM1_00839 | SRM1_01059 | Catabolite repressor/activator. | Phosphoenolpyruvate-protein phosphotransferase. | 0.908 |
| cra | ptsI_3 | SRM1_00839 | SRM1_04625 | Catabolite repressor/activator. | Phosphoenolpyruvate-protein phosphotransferase. | 0.910 |
| fbp_1 | fda | SRM1_00404 | SRM1_05353 | Fructose-1,6-bisphosphatase class 1. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.995 |
| fbp_1 | lacC | SRM1_00404 | SRM1_00841 | Fructose-1,6-bisphosphatase class 1. | Tagatose-6-phosphate kinase. | 0.963 |
| fbp_1 | pgi | SRM1_00404 | SRM1_04859 | Fructose-1,6-bisphosphatase class 1. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.990 |
| fbp_1 | ptsI_1 | SRM1_00404 | SRM1_00840 | Fructose-1,6-bisphosphatase class 1. | Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. | 0.848 |
| fbp_1 | ptsI_2 | SRM1_00404 | SRM1_01059 | Fructose-1,6-bisphosphatase class 1. | Phosphoenolpyruvate-protein phosphotransferase. | 0.453 |
| fbp_1 | ptsI_3 | SRM1_00404 | SRM1_04625 | Fructose-1,6-bisphosphatase class 1. | Phosphoenolpyruvate-protein phosphotransferase. | 0.453 |
| fbp_1 | tal | SRM1_00404 | SRM1_03757 | Fructose-1,6-bisphosphatase class 1. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.975 |
| fda | fbp_1 | SRM1_05353 | SRM1_00404 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Fructose-1,6-bisphosphatase class 1. | 0.995 |
| fda | fruA | SRM1_05353 | SRM1_00842 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | PTS system fructose-specific EIIBC component. | 0.990 |
| fda | lacC | SRM1_05353 | SRM1_00841 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Tagatose-6-phosphate kinase. | 0.980 |
| fda | pgi | SRM1_05353 | SRM1_04859 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.995 |
| fda | ptsI_1 | SRM1_05353 | SRM1_00840 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. | 0.984 |
| fda | ptsI_2 | SRM1_05353 | SRM1_01059 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Phosphoenolpyruvate-protein phosphotransferase. | 0.970 |
| fda | ptsI_3 | SRM1_05353 | SRM1_04625 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Phosphoenolpyruvate-protein phosphotransferase. | 0.970 |
| fda | ptsN | SRM1_05353 | SRM1_00902 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Nitrogen regulatory protein. | 0.738 |