| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysE_1 | cysE_2 | SRM1_00301 | SRM1_04658 | Serine acetyltransferase. | Serine acetyltransferase. | 0.961 |
| cysE_1 | glyA2_1 | SRM1_00301 | SRM1_04928 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| cysE_1 | glyA2_2 | SRM1_00301 | SRM1_05308 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
| cysE_1 | hom | SRM1_00301 | SRM1_01082 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.942 |
| cysE_1 | ilvA_2 | SRM1_00301 | SRM1_05530 | Serine acetyltransferase. | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.926 |
| cysE_1 | pssA | SRM1_00301 | SRM1_02745 | Serine acetyltransferase. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.918 |
| cysE_1 | serB_1 | SRM1_00301 | SRM1_00558 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.969 |
| cysE_1 | tdcG | SRM1_00301 | SRM1_00964 | Serine acetyltransferase. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.957 |
| cysE_1 | trpA | SRM1_00301 | SRM1_00163 | Serine acetyltransferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
| cysE_1 | trpB | SRM1_00301 | SRM1_00162 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
| cysE_2 | cysE_1 | SRM1_04658 | SRM1_00301 | Serine acetyltransferase. | Serine acetyltransferase. | 0.961 |
| cysE_2 | glyA2_1 | SRM1_04658 | SRM1_04928 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| cysE_2 | glyA2_2 | SRM1_04658 | SRM1_05308 | Serine acetyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| cysE_2 | hom | SRM1_04658 | SRM1_01082 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.972 |
| cysE_2 | ilvA_2 | SRM1_04658 | SRM1_05530 | Serine acetyltransferase. | L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.959 |
| cysE_2 | pssA | SRM1_04658 | SRM1_02745 | Serine acetyltransferase. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.955 |
| cysE_2 | serB_1 | SRM1_04658 | SRM1_00558 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.982 |
| cysE_2 | tdcG | SRM1_04658 | SRM1_00964 | Serine acetyltransferase. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.958 |
| cysE_2 | trpA | SRM1_04658 | SRM1_00163 | Serine acetyltransferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.957 |
| cysE_2 | trpB | SRM1_04658 | SRM1_00162 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.956 |
