| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arsC_2 | gcvP_1 | SRM1_04174 | SRM1_04328 | Arsenate reductase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.627 |
| arsC_2 | gcvP_2 | SRM1_04174 | SRM1_05571 | Arsenate reductase. | Glycine dehydrogenase (decarboxylating). | 0.627 |
| arsC_2 | rpoA | SRM1_04174 | SRM1_05155 | Arsenate reductase. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.693 |
| arsC_2 | spxA | SRM1_04174 | SRM1_01122 | Arsenate reductase. | Regulatory protein Spx; Belongs to the ArsC family. | 0.647 |
| dapD | dapL | SRM1_01121 | SRM1_01126 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | LL-diaminopimelate aminotransferase. | 0.995 |
| dapD | glnD | SRM1_01121 | SRM1_01127 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.737 |
| dapD | nhaK | SRM1_01121 | SRM1_01123 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | Sodium, potassium, lithium and rubidium/H(+) antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.791 |
| dapD | rpsB | SRM1_01121 | SRM1_01129 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.694 |
| dapD | spxA | SRM1_01121 | SRM1_01122 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | Regulatory protein Spx; Belongs to the ArsC family. | 0.869 |
| dapD | sufE | SRM1_01121 | SRM1_01119 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | Cysteine desulfuration protein SufE. | 0.823 |
| dapL | dapD | SRM1_01126 | SRM1_01121 | LL-diaminopimelate aminotransferase. | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.995 |
| dapL | gcvP_1 | SRM1_01126 | SRM1_04328 | LL-diaminopimelate aminotransferase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.489 |
| dapL | gcvP_2 | SRM1_01126 | SRM1_05571 | LL-diaminopimelate aminotransferase. | Glycine dehydrogenase (decarboxylating). | 0.489 |
| dapL | glnD | SRM1_01126 | SRM1_01127 | LL-diaminopimelate aminotransferase. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.863 |
| dapL | rpsB | SRM1_01126 | SRM1_01129 | LL-diaminopimelate aminotransferase. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.761 |
| dapL | spxA | SRM1_01126 | SRM1_01122 | LL-diaminopimelate aminotransferase. | Regulatory protein Spx; Belongs to the ArsC family. | 0.694 |
| dapL | sufE | SRM1_01126 | SRM1_01119 | LL-diaminopimelate aminotransferase. | Cysteine desulfuration protein SufE. | 0.694 |
| gcvP_1 | arsC_2 | SRM1_04328 | SRM1_04174 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Arsenate reductase. | 0.627 |
| gcvP_1 | dapL | SRM1_04328 | SRM1_01126 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | LL-diaminopimelate aminotransferase. | 0.489 |
| gcvP_1 | gcvP_2 | SRM1_04328 | SRM1_05571 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine dehydrogenase (decarboxylating). | 0.999 |
